Changelog

2024.3.0

This release is breaking for ALL versions of MinKNOW <= 6 and no longer supports Guppy.

  1. Introducing support for MinKNOW >=6.0.0 and deprecating support for earlier versions.

  2. Removing support for legacy guppy base caller and only supporting Dorado in future.

  3. Optimising batch sending to the base caller through the use of pass_reads rather than pass_read

  4. Adding the new strand classifications as used by MinKNOW, including strand2 and short.

2024.2.0

  1. Add a dorado base-caller which addressed issue #347 - chiefly in Dorado 7.3.9 ONT have moved to ont-pybasecall-client-lib, and connections from ont_pyguppy_client_lib raise Connection error. ...  LOAD_CONFIG. Reply: INVALID_PROTOCOL (#344)

  2. Adds version checking for MinKNOW and Guppy/Dorado, logs if not compatibile (#351)

2024.1.0

  1. bug fix type for --wait-on-ready type and actual function (#327), (#323)

  2. mutiple suffix .mmi support (#330)

  3. Change the default unblock_duration on the Analysis class to use DEFAULT_UNBLOCK value defined in _cli_args.py. Change type on the Argparser for --unblock-duration to float. (#313)

  4. Big dog Duplex feature - adds ability to select duplex reads that cover a target region. See pull request for details (#324)

2023.1.1

  1. Fix Readme Logo link 🥳 (#296)

  2. Fix bug where we had accidentally started requiring barcoded TOMLs to specify a region. Thanks to @jamesemery for catching this. (#299)

  3. Correctly handle overriding a decision in internal statistics tracking. (#299)